Chronic obstructive pulmonary disease and obstructive sleep apnoea overlap: co-existence, co-morbidity, or causality?. Issue 6 (21st November 2022)

• Record Type: Journal Article
• Authors: O'Neill, Emily; Ryan, Silke; McNicholas, Walter T.
• Is Part Of: Current opinion in pulmonary medicine. Volume 28:Issue 6(2022)
• Page Start: 543
• Page End: 551
• Publication Date: 2022-11-21
• Subjects: cardiovascular events -- chronic obstructive pulmonary disease -- nocturnal desaturation -- obstructive sleep apnoea -- overlap syndrome; Respiratory organs -- Diseases -- Periodicals; 616.24
• DOI: 10.1097/MCP.0000000000000922
• Languages: English
• ISSNs: 1070-5287

Abstract

Abstract : Purpose of review: The chronic obstructive pulmonary disease and obstructive sleep apnoea overlap syndrome is associated with higher morbidity and mortality rates than either disease alone. There is evidence of a bidirectional relationship between the two conditions, with the overlap syndrome encompassing a spectrum of clinical phenotypes. Recent findings: This review examines the evidence for the various factors that determine the overlap syndrome, the impact overlap syndrome has on co-morbidities, and implications for diagnosis and treatment. Summary: The accurate diagnosis of the overlap syndrome is critical given its implications for treatment optimisation and reduction in healthcare utilisation and costs.