Therapeutic Effects of 4 Surgical Approaches for Small Gastrointestinal Stromal Tumors: A Network Meta-analysis. Issue 5 (10th October 2022)

• Record Type: Journal Article
• Authors: Yu, Zhiyuan; Tu, Huaiyu; Liang, Chen; Qiu, Shuzhong; Dong, Xiaoyu; Zhang, Yonghui; Ma, Chao; Li, Peiyu
• Is Part Of: Surgical laparoscopy endoscopy & percutaneous techniques. Volume 32:Issue 5(2022)
• Page Start: 606
• Page End: 615
• Publication Date: 2022-10-10
• Subjects: endoscopic operation -- laparoscopic surgery -- laparoscopic endoscopic cooperative surgery -- gastrointestinal stromal tumors -- network meta-analysis; Endoscopic surgery -- Periodicals; Laparoscopic surgery -- Periodicals; Endoscopy -- Periodicals; Laparoscopy -- Periodicals; 617.550597
• DOI: 10.1097/SLE.0000000000001076
• Languages: English
• ISSNs: 1530-4515

Abstract

Abstract : This study aims to systematically evaluate the efficacy of endoscopic resection (ER), laparoscopic resection (LR), laparoscopic endoscopic cooperative surgery (LECS), and open surgery (OpS) for gastrointestinal stromal tumors with small diameters (≤5 cm). Relevant studies were collected through Pubmed, Cochrane Library, and Embase databases. Operative time, hospital stays, time to liquid diet, intraoperative bleeding, and complications were used as outcome indicators for meta-analysis. Twenty-four retrospective cohort studies with 2406 participants were analyzed. LR and OpS groups had longer operating time than the ER group. ER, LECS, and LR groups had decreased lengths of hospital stay than the OpS group. Moreover, patients in LR and LECS groups had fewer complications than those in the OpS group. Endoscopic operation for small gastrointestinal stromal tumors contributes to shortened lengths of surgery and hospital stay. This reduces intraoperative blood loss and promotes gastroenteric functional recovery without increasing the risk of complications or tumor recurrence.