Thoracic amyloidomas: Two case reports of an evasive diagnosis. (6th May 2014)

• Record Type: Journal Article
• Authors: Cresner, Rosie; Mahmood, Shameem; Chen, Jane; Rowan, Camilla; Wechalekar, Ashutosh D
• Is Part Of: JRSM open. Volume 5:Number 6(2014:Jun.)
• Publication Date: 2014-05-06
• Subjects: Medicine -- Periodicals; Medicine -- Great Britain -- Periodicals; 610.5
• DOI: 10.1177/2054270414527280
• Languages: English
• ISSNs: 2054-2704

Abstract

Lesson: Amyloidosis is a rare differential diagnosis of a mass detected in the chest. Amyloidoma is caused by a local proliferation of clonal B-cells secreting an unstable immunoglobulin light chain which accumulates. FDG-PET scan are useful but not specific. Treatment is generally by local resection for treatment of symptoms. We report two cases of amyloidomas, which are rare entities characterised by large local amyloid deposits. These can occur in the upper respiratory tract, soft tissues and central nervous system. 1