Antibody titers and neutralizing activity in cases of COVID-19 after a single dose of vaccination. Issue 12 (December 2022)

• Record Type: Journal Article
• Authors: Okumura, Nobumasa; Saito, Sho; Takamatsu, Yuki; Takeuchi, Junko S.; Asai, Yusuke; Sanada, Mio; Iwamoto, Noriko; Maeda, Kenji; Mitsuya, Hiroaki; Ohmagari, Norio
• Is Part Of: Journal of infection and chemotherapy. Volume 28:Issue 12(2022)
• Page Start: 1704
• Page End: 1706
• Publication Date: 2022-12
• Subjects: SARS-CoV-2 -- Antibody titers -- Neutralizing titer -- Vaccination; Chemotherapy -- Periodicals; Infection -- Periodicals; Communicable diseases -- Chemotherapy -- Periodicals; 615.5805
• DOI: 10.1016/j.jiac.2022.08.026
• Languages: English
• ISSNs: 1341-321X

Abstract

Abstract: Vaccines for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) have shown high efficacy in preventing the onset of disease. However, the immune response to infection immediately after the first vaccination remains unknown. We examined the anti-SARS-CoV-2-binding-antibody titers and neutralizing activity in patients who developed coronavirus disease 2019 after the first vaccination. The amount of anti-SARS-CoV-2-binding antibodies and neutralizing activity drastically increased from the first to the second collection. Our results may provide important data on the course of immune response following vaccination.