CD3 and CD20 Expression in Titanium vs Zirconia Peri-Implant Soft Tissues: A Human Study. (January 2013)

• Record Type: Journal Article
• Authors: Bambini, F.; Santarelli, A.; Marzo, G.; Rubini, C.; Orsini, G.; Di Iorio, D.; Russo, L. Lo; Muzio, L. Lo
• Is Part Of: European journal of inflammation. Volume 11:Number 1(2013)
• Page Start: 305
• Page End: 310
• Publication Date: 2013-01
• Subjects: CD3 -- CD20 -- peri-implant inflammation -- human study; Inflammation -- Periodicals; Anti-Inflammatory Agents -- therapeutic use -- Periodicals; Immunotherapy -- Periodicals; Inflammation -- Periodicals; Anti-inflammatory agents -- Periodicals; Immunotherapy -- Periodicals; Anti-inflammatory agents; Immunotherapy; Inflammation; Periodicals; 616.0473
• DOI: 10.1177/1721727X1301100133
• Languages: English
• ISSNs: 1721-727X

Abstract

The aim of this study was to investigate the presence of an inflammatory infiltrate in the peri-implant soft tissue of single-implant crowns supported by either zirconia or titanium abutments in healthy subjects. Serial sections from formalin-fixed, paraffin-embedded blocks from peri-implant mucosa of 25 patients were immunohistochemically analyzed for CD3 and CD20 lymphocyte marker expression. The results showed that levels of T cells (CD3) were higher around zirconia than titanium abutments (p<0.05). On the contrary, the levels of B cells (CD20) were found higher around titanium abutment in comparison with the zirconia abutment. These differences were statistically significant (p<0.05).