Erythema Multiforme Major after Whole Brain Radiotherapy: A Case of Emar Syndrome?. (May 2013)

• Record Type: Journal Article
• Authors: Bottoni, U.; Nisticò, S.; Amoruso, G.F.; Sacco, A.; Arcidiacono, V.; Calvieri, S.
• Is Part Of: European journal of inflammation. Volume 11:Number 2(2013)
• Page Start: 535
• Page End: 537
• Publication Date: 2013-05
• Subjects: erythema multiforme -- Stevens-Johnson syndrome -- whole brain radiotherapy (WBRT) -- metastatic breast carcinoma -- phenobarbital -- exemestane -- methylprednisolone -- EMPACT (Erythema Multiforme associated with Phenytoin and Cranial radiation Therapy) syndrome; Inflammation -- Periodicals; Anti-Inflammatory Agents -- therapeutic use -- Periodicals; Immunotherapy -- Periodicals; Inflammation -- Periodicals; Anti-inflammatory agents -- Periodicals; Immunotherapy -- Periodicals; Anti-inflammatory agents; Immunotherapy; Inflammation; Periodicals; 616.0473
• DOI: 10.1177/1721727X1301100224
• Languages: English
• ISSNs: 1721-727X

Abstract

We report the case of a woman with a 4-year history of metastatic breast carcinoma presenting a large erosive area on her scalp plus erosive lesions on the lips and in the mouth and erythematous plaques with vesicles on the trunk and upper limbs. In this case, contrary to other reports, the most important trigger for this syndrome was radiotherapy rather than the systemic medications administered. Therefore we propose the term EMAR (erythema multiforme associated to radiotherapy) to describe this case.