Preserving stroke penumbra by targeting lipid signalling. Issue 1 (January 2023)

• Record Type: Journal Article
• Authors: Achón Buil, Beatriz; Rust, Ruslan
• Is Part Of: Journal of cerebral blood flow & metabolism. Volume 43:Issue 1(2023)
• Page Start: 167
• Page End: 169
• Publication Date: 2023-01
• Subjects: Autotaxin -- hyperexcitability -- ischemia -- penumbra -- therapy; Cerebral circulation -- Periodicals; Brain -- Metabolism -- Periodicals; Brain -- Blood-vessels -- Periodicals; Cerebrovascular disease -- Periodicals; 612.824
• DOI: 10.1177/0271678X221121853
• Languages: English
• ISSNs: 0271-678X

Abstract

Pharmacological inhibition of astrocytic enzyme autotaxin rescues the stroke penumbra in mice and improves functional recovery, indicating therapeutic potential.