Supramolecular Catalysts for Organic Synthesis: Preparation and Applications of Cyclodextrins and Calixarenes in C−C Cross‐Coupling Reactions. Issue 35 (20th September 2022)

• Record Type: Journal Article
• Authors: Lima, Carolina G. S.; Pauli, Fernanda P.; Madriaga, Vinicius G.; Amaral, Adriane A. P.; Graciano, Isabela A.; Meira, Vinicius L.; da S. M. Forezi, Luana; Ferreira, Vitor F.; de M. Lima, Thiago; de Carvalho da Silva, Fernando
• Is Part Of: European journal of organic chemistry. Volume 2022:Issue 35(2022)
• Page Start: n/a
• Page End: n/a
• Publication Date: 2022-09-20
• Subjects: Calixarenes -- Catalysis -- Cyclodextrins -- Green chemistry; Chemistry, Organic -- Periodicals; Organic compounds -- Synthesis -- Periodicals; Bioorganic chemistry -- Periodicals; Chemistry, Physical organic -- Periodicals; 547
• DOI: 10.1002/ejoc.202200904
• Languages: English
• ISSNs: 1434-193X

Abstract

Abstract: Reactions that promote the formation of carbon–carbon bonds are of great importance in organic synthesis, since they transform available, relatively inexpensive, and small organic molecules into more complex ones. One of the main protocols used for these transformations are cross‐coupling reactions, and due to their versatility and applications, several efforts have been devoted recently to developing catalysts for such reactions. Supramolecular chemistry has become a major player in this field and encompasses approaches that range from the synthesis of intricate complex architectures that may mimic enzymes, the slight structural modification of commercially available scaffolds, or even repurposing highly available materials such as agarose. This Review discusses the development of supramolecular catalysts for cross‐coupling reactions, focusing mostly on the Suzuki, Heck and Sonogashira reactions promoted by such assemblies. Abstract : In the past decades, supramolecular catalysis has arisen as an important tool in the formation of C−C bonds through cross‐coupling reactions. In this Review, the concepts related to the use of the most explored supramolecular scaffolds, that is, cyclodextrins and calixarenes, in such processes are discussed.