Toxicology properties of commercial anti‐mosquitos and their effects on carboxyhemoglobin and malondialdehyde levels. Issue 1 (21st February 2022) - Andini, Ary
Abstract: Exposure of carbon monoxide (CO) released by insect repellent has a negative impact on health by forming carboxyhemoglobin (CO‐Hb) as a trigger for oxidative stress in the human body. Therefore, the objective of the study was to investigate the effect of commercial anti‐mosquitos on CO‐Hb and malondialdehyde (MDA) levels in the blood. Effect of electric spray, coils, and electric mats on CO‐Hb and MDA levels in blood was evaluated using male Wistar rats (8 h per day) and monitored for 20 days. The study found that the highest increase in CO‐Hb and CO‐Hb levels in the blood was observed when exposed to electric spray formula compared to other anti‐mosquitos. In addition, the highest increase in MDA levels also occurred when exposed to the electric spray. Statistical analysis revealed that there was a significant relationship between CO‐Hb and MDA levels in the blood ( p ‐value = 0.000). High CO‐Hb levels in the blood could stimulate oxidative stress and lead to cell damage in the body.