The global, regional, and national burden of nasopharyngeal carcinoma and its attributable risk factors in 204 countries and territories, 1990–2019. (3rd August 2022)

• Record Type: Journal Article
• Authors: Zhang, Yuna; Cao, Yujie; Luo, Lin; Li, Jun; Wang, Liuqian; Lu, Yaqin; Gu, Shanshan; Deng, Hongxia; Shen, Zhisen
• Is Part Of: Acta oto-laryngologica. Volume 142:Number 7/8(2022)
• Page Start: 590
• Page End: 609
• Publication Date: 2022-08-03
• Subjects: Global Burden of Diseases -- incidence -- DALY -- death -- risk -- nasopharyngeal carcinom; Otolaryngology -- Periodicals; Ear -- Diseases -- Periodicals; Throat -- Diseases -- Periodicals; Otolaryngology -- Electronic Resources; Otorhinolaryngologic Diseases; 617.8
• DOI: 10.1080/00016489.2022.2111711
• Languages: English
• ISSNs: 0001-6489

Abstract

Abstract: Background: Nasopharyngeal carcinoma (NPC) is uncommon in most areas of the world but poses a significant public health burden in endemic regions. Objectives: We provide an overview of the most recent global epidemiology of nasopharyngeal cancer (NPC). Methods: We estimated the burden of NPC in 204 countries and territories by age, sex, and Socio-Demographic Index (SDI) from 1990 to 2019. Results: At the GBD regional level, the most severe age-standardized incidence in 2019 occurred in East Asia. From 1990 to 2019, the East Asia and High-income Asia Pacific had the greatest increase in percentage in age-standardized incidence. Central Asia and the Caribbean had the greatest increase in percentage in age-standardized disability-adjusted life-years (DALY) and death rates. At the national level, Cabo Verde, Romania, and the Cyprus reported the largest percentage increases in the age-standardized incidence. Cabo Verde, Romania, and Jamaica reported the largest increases in the age-standardized DALY and death rates. Conclusions: The global age-standardized incidence of NPC increased globally between 1990 and 2019, especially in the East Asia.