Migraine and frequent tension-type headache are not associated with multiple sclerosis in a Norwegian case-control study. (December 2016)

• Record Type: Journal Article
• Authors: Gustavsen, MW; Celius, EG; Winsvold, BS; Moen, SM; Nygaard, GO; Berg-Hansen, P; Lie, BA; Zwart, J-A; Harbo, HF
• Is Part Of: Multiple sclerosis journal, experimental, translational and clinical. Volume 2(2016)
• Publication Date: 2016-12
• Subjects: Multiple sclerosis -- migraine -- tension-type headache -- case-control study; Multiple sclerosis -- Periodicals; 616.834
• DOI: 10.1177/2055217316682976
• Languages: English
• ISSNs: 2055-2173

Abstract

Background: Inconsistent results have been obtained with regard to headache comorbidity in multiple sclerosis (MS). Objective: Investigate the one-year prevalence of migraine and tension-type headache (TTH) in Norwegian MS patients and relate this to clinical parameters. Methods: A questionnaire concerning headache was administered to 756 MS patients and 1090 controls and used to determine the one-year prevalence of migraine and frequent TTH. Results: No significant differences were seen between patients and controls or between patients with different disease course. Less migraine was observed in patients with Expanded Disability Status Scale score (EDSS) ≥4.0. Conclusions: This case-control study does not support an association between migraine or TTH and MS.