Efficient synthesis of 3-hydroxy chromones via oxidative cyclization mediated by lipase. Issue 3 (3rd July 2022)

• Record Type: Journal Article
• Authors: Li, Jiapeng; Yu, Yue; Xu, Yaning; Li, Fengxi; Liu, Yuqi; Sun, Yifei; Wang, Chunyu; Chen, Peng; Wang, Lei
• Is Part Of: Green chemistry letters and reviews. Volume 15:Issue 3(2022)
• Page Start: 689
• Page End: 694
• Publication Date: 2022-07-03
• Subjects: Lipase -- catalytic promiscuity -- 3-hydroxy chromones -- oxidation; Green chemistry -- Periodicals; 540
• DOI: 10.1080/17518253.2022.2127331
• Languages: English
• ISSNs: 1751-8253

Abstract

ABSTRACT: In this work, an efficient synthesis of 3-hydroxy chromones was accomplished through oxidative cyclization mediated by lipase. This enzymatic process has salient features of environmental friendliness, mild reaction condition, satisfactory yield, green reusable biocatalyst, and short reaction time. The proposed method expands the application of lipase in organic synthesis. GRAPHICAL ABSTRACT: UF0001