A new sesquiterpene from South African wild ginger (Siphonochilus aethiopicus (Schweinf) B.L. Burtt). Issue 19 (21st September 2022)

• Record Type: Journal Article
• Authors: Al-Tannak, Naser F.; Anyam, John V.; Igoli, Ngozichukwuka P.; Gray, Alexander I.; Alzharani, Mansour A.; Igoli, John O.
• Is Part Of: Natural product research. Volume 36:Issue 19(2022)
• Page Start: 4943
• Page End: 4948
• Publication Date: 2022-09-21
• Subjects: Furanoeudesmane -- eusdesmane sesquiterpenoids -- Siphonochilus sp -- spectroscopic analysis; Natural products -- Periodicals; Natural products -- Research -- Periodicals; Biological Factors -- Periodicals; Biological Products -- Periodicals; 547
• DOI: 10.1080/14786419.2021.1914029
• Languages: English
• ISSNs: 1478-6419

Abstract

Abstract: A new eusdesmane sesquiterpenoid, characterised as 5-acetoxy-9a β -hydroxy-4aαH-3, 5α, 8a β -trimethyl-4, 4a, 6, 7, 8a, 9-hexahydronaphtho-([2, 3 b]-dihydrofuran-2-one)-8-one or phaeusmane F acetate (1 ) has been isolated from the rhizomes of the South African variety of wild ginger ( iphonochilus aethiopicus (Schweinf) B.L. Burtt). The compound was obtained after a series of column and gel filtration chromatography. Its structure was elucidated by NMR and Mass-Spectrometric analyses, including 1 D-, 2 D-NMR and HR-LCMS. This is an initial report of the compound from a Siphonochilus sp . Previously isolated similar compounds from the plant material were 4aαH-3, 5α, 8a β -trimethyl-4, 4a, 8a, 9-tetrahydronaphtho[2, 3b]-furan-8-one (siphonochilone) (2 ), 9a β -hydroxy-4aαH-3, 5α, 8a β -trimethyl-4, 4a, 8a, 9-tetrahydronaphtho-([2, 3b]-dihydrofuran-2-one)-8-one (3 ), 4aαH-3, 5α, 8a β -trimethyl-4, 4a, 8a, 9-tetrahydronaphtho-([2, 3b]-dihydrofuran-2-one)-8-one (4 ), 2-hydroxy-4aαH-3, 5α, 8a β -trimethyl-4, 4a, 8a, 9-tetrahydro-naphtho[2, 3b]- furan-8(5H)-one (5 ), 4aαH-3, 5α, 8a β -trimethyl-4, 4a, 8a-trihydronaphtho-([2, 3b]-dihydrofuran-2-one)-8-one (6 ).