Risk Factors for Colistin-Resistant Carbapenem-Resistant Klebsiella pneumoniae in the Postacute Care Setting. (2nd September 2022)

• Record Type: Journal Article
• Authors: Zhang, Helen L; Han, Jennifer H; Lapp, Zena; Snitkin, Evan; Goldstein, Ellie J C; Muldoon, Sean; Tolomeo, Pam; Lautenbach, Ebbing
• Is Part Of: Open forum infectious diseases. Volume 9:Number 9(2022)
• Publication Date: 2022-09-02
• Subjects: carbapenem-resistant Klebsiella pneumoniae -- colistin -- long-term acute care hospitals; Communicable diseases -- Periodicals; Medical microbiology -- Periodicals; Infection -- Periodicals; 616.9
• DOI: 10.1093/ofid/ofac452
• Languages: English
• ISSNs: 2328-8957

Abstract

Abstract: We assessed risk factors for colistin resistance among carbapenem-resistant Klebsiella pneumoniae (CRKP) from 375 patients in long-term acute care hospitals. Recent colistin or polymyxin B exposure was associated with increased odds of colistin resistance (adjusted odds ratio = 1.11 per day of exposure, 95% confidence interval = 1.03–1.19, P = .007). Abstract : Among patients in long-term acute care hospitals with carbapenem-resistant Klebsiella pneumoniae (CRKP) infection or colonization, recent colistin or polymyxin B exposure was associated with increased odds of colistin-resistant CRKP.