Top advances of the year: Pediatric oncology. Issue 20 (8th September 2022)

• Record Type: Journal Article
• Authors: Pappo, Alberto S.; Karol, Seth E.; Bertrand, Kelsey C.
• Is Part Of: Cancer. Volume 128:Issue 20(2022)
• Page Start: 3593
• Page End: 3596
• Publication Date: 2022-09-08
• Subjects: brain tumor -- leukemia -- recurrent disease -- residual disease -- solid tumor; Cancer -- Periodicals; Cancer -- Cytopathology -- Periodicals; 616.99405
• DOI: 10.1002/cncr.34425
• Languages: English
• ISSNs: 0008-543X

Abstract

Abstract: Accelerated discovery and collaborative research continue to highlight the remarkable progress that has been made in the diagnosis and treatment of pediatric cancers. This manuscript highlights important discoveries on how precision oncology is being incorporated into the diagnosis and treatment of childhood cancer at the national level to identify promising new therapies using a tumor‐agnostic approach. In addition, we have highlighted three articles that incorporate genomics and cell‐free DNA to better classify, monitor and incorporate risk‐based therapies for children with medulloblastoma. Finally, we highlighted the important role of monclonal antiobody therapy in the treatment of recurrent B‐cell leukemia and newly diagnosed high‐risk neuroblastoma. Abstract : This commentary summarizes the top advances in pediatric cancer over the past 12 months.