Skin anti‐inflammatory activity of water‐soluble fullerene nanocomposites encompassed by sodium hyaluronate. (27th December 2021)

• Record Type: Journal Article
• Authors: Wang, Tao; Li, Hui; Xu, Zhe; Wang, Chunru
• Is Part Of: Journal of cosmetic dermatology. Volume 21:Number 9(2022)
• Page Start: 4016
• Page End: 4019
• Publication Date: 2021-12-27
• Subjects: fullerene -- nanocomposites -- skin anti‐inflammatory -- sodium hyaluronate; Skin -- Diseases -- Treatment -- Periodicals; Lasers in surgery -- Periodicals; Skin -- Pathophysiology -- Periodicals; Surgery, Plastic -- Periodicals; 616.5
• DOI: 10.1111/jocd.14711
• Languages: English
• ISSNs: 1473-2130

Abstract

Abstract: Fullerene is one of the nanomaterials that has a value in dermatological and cosmetic applications. In present work, we designed and prepared water‐soluble nano‐scale C60 encompassed by sodium hyaluronate. The rat ear swelling test was utilized to evaluate the anti‐inflammatory activity of encompassed C60. The measurement shows that the rat ear swelling rate of C60 administrated group is reduced to less than 10%, which shows good anti‐inflammatory activity. Its anti‐inflammatory activity is roughly calculated as 10 times than that of dipotassium glycyrrhizinate and five times than that of tanshinone. In conclusion, the fullerenes encapsulated by sodium hyaluronate have great potential in skin care and auxiliary treatment of dermatosis.