Eucryphia cordifolia extracts: Phytochemical screening, antibacterial and antioxidant activities. Issue 16 (29th July 2022)

• Record Type: Journal Article
• Authors: Viteri, Rafael; Giordano, Ady; Montenegro, Gloria; Zacconi, Flavia
• Is Part Of: Natural product research. Volume 36:Issue 16(2022)
• Page Start: 4177
• Page End: 4181
• Publication Date: 2022-07-29
• Subjects: Eucryphia cordifolia -- antibacterial -- antioxidant activity -- phenols content -- flavonoids; Natural products -- Periodicals; Natural products -- Research -- Periodicals; Biological Factors -- Periodicals; Biological Products -- Periodicals; 547
• DOI: 10.1080/14786419.2021.1960525
• Languages: English
• ISSNs: 1478-6419

Abstract

Abstract: Eucryphia cordifolia is a native and dominant species from the Temperate Forest in the southern region of Chile. It is a crucial melliferous species producing unifloral honey with outstanding antibacterial properties with great commercial value at international markets. A phytochemical screening was developed by colorimetric and gravimetric methods. Antioxidant activities were assessed by using 2, 2-diphenyl-1-picrylhydrazyl (DPPH), 2, 2-azino-bis-3-ethylbenzothiazoline-6-sulfonic acid (ABTS), and ferric ion reducing antioxidant power (FRAP) method. The minimum bactericidal concentration (MBC) was the method used to determine the antibacterial activity. The results revealed the highest antioxidant activity for the methanolic extracts of branches (IC50 35.7 µg/mL for DPPH, IC50 11.0 µg/mL for ABTS, and 4.6 mM FeSO4 ·7H2 O/g in FRAP), attributed to its high content of total phenols (332.8 mg GAE/g). The quantification of the MBC led to values in the range of 0.78–12.5 mg/mL for S. aureus and S. pyogenes, and 6.25–50 mg/mL for E. coli and P. aeruginosa, respectively. The presented work provides valuable first in vitro evidence regarding the potential application of E. cordifolia extracts as antioxidants and antibacterial agents in the nutraceutical and phytopharmaceutical industry. Graphical Abstract: UF0001