Extraction of patient-specific boundary conditions from 4D-DSA and their influence on CFD simulations of cerebral aneurysms. Issue 11 (15th August 2022)

• Record Type: Journal Article
• Authors: Uchiyama, Yuya; Fujimura, Soichiro; Takao, Hiroyuki; Ono, Hiroshi; Katayama, Keigo; Suzuki, Takashi; Ishibashi, Toshihiro; Otani, Katharina; Karagiozov, Kostadin; Fukudome, Koji; Murayama, Yuichi; Yamamoto, Makoto
• Is Part Of: Computer methods in biomechanics and biomedical engineering. Volume 25:Issue 11(2022)
• Page Start: 1222
• Page End: 1234
• Publication Date: 2022-08-15
• Subjects: Blood flow simulation -- haemodynamics -- cerebral aneurysm -- inflow condition -- 4D-DSA; Biomechanics -- Data processing -- Periodicals; Biomedical engineering -- Periodicals; Biomechanics -- Periodicals; Biomedical Engineering -- methods -- Periodicals; Computing Methodologies -- Periodicals; 612.7
• DOI: 10.1080/10255842.2021.2005035
• Languages: English
• ISSNs: 1025-5842

Abstract

Abstract: We developed a new technique for extracting patient-specific inflow conditions, such as the pulse cycle duration and blood flow velocity, from four-dimensional digital subtraction angiography images and experimentally examined its validity. The maximum error between the values extracted by the technique and measured values was 14.3%. We performed blood flow simulations and calculated representative haemodynamic parameters. The maximum differences between the parameters obtained using general and patient-specific inflow conditions were approximately 400%, 150%, and 50% for the velocity, normalised wall shear stress, and pressure loss coefficient, respectively. These results indicate that patient-specific conditions are critical for accurately reproducing aneurysmal haemodynamics.