Pleural decortication and hyperthermic intrathoracic chemotherapy for pseudomyxoma. (31st December 2022)

• Record Type: Journal Article
• Authors: Proesmans, Viktor; Vandaele, Tom; Van Slambrouck, Jan; Wolthuis, Albert; D´Hoore, André; Dekervel, Jeroen; Van Cutsem, Eric; Dresen, Raphaëla; De Hertogh, Gert; Degezelle, Karlien; Van Raemdonck, Dirk; Nafteux, Philippe; Ceulemans, Laurens J.
• Is Part Of: International journal of hyperthermia. Volume 39:Number 1(2022)
• Page Start: 1153
• Page End: 1157
• Publication Date: 2022-12-31
• Subjects: HITHOC -- pleural decortication -- pseudomyxoma peritonei; Thermotherapy -- Periodicals; 615.832
• DOI: 10.1080/02656736.2022.2104938
• Languages: English
• ISSNs: 0265-6736

Abstract

Abstract: Aim: Pleural dissemination of pseudomyxoma peritonei (PMP) is an extremely rare diagnosis, for which no standard therapy is available. Methods: We describe the successful treatment of a 67-year-old male diagnosed with left-sided intrapleural dissemination of PMP (low-grade appendiceal mucinous neoplasm), 2 years after treatment of abdominal PMP with cytoreductive surgery (CRS) and hyperthermic intra-peritoneal chemotherapy. Treatment consisted of extended pleural decortication (ePD) and oxaliplatin-based hyperthermic intrathoracic chemotherapy (HITHOC). The patient is doing well without complications or signs of recurrence, 26 months after thoracic surgery. Conclusion: ePD in combination with HITHOC is a valuable treatment for thoracic PMP.