Effects of acute endurance exercise on follistatin-like 1 and apelin in the circulation and metabolic organs in rats. (3rd September 2022)

• Record Type: Journal Article
• Authors: Kon, Michihiro; Tanimura, Yuko; Yoshizato, Hideo
• Is Part Of: Archives of physiology and biochemistry. Volume 128:Number 5(2022)
• Page Start: 1254
• Page End: 1258
• Publication Date: 2022-09-03
• Subjects: Acute exercise -- adipo-myokine -- energy metabolism -- insulin sensitivity; Physiology -- Periodicals; Biochemistry -- Periodicals; Biophysics -- Periodicals; Biochemistry; Physiology; 571
• DOI: 10.1080/13813455.2020.1764050
• Languages: English
• ISSNs: 1381-3455

Abstract

Abstract: Context: Follistatin-like 1 (FSTL1) and apelin exert a favourable effect on energy metabolism. Objective: We examined the effects of acute endurance exercise on the levels of FSTL1 and apelin in the serum and metabolic organs of rats. Methods: Rats were divided into two groups: a sedentary control (CON, n = 8) group and exercise (EX, n = 8) group. The EX group was made to run on a treadmill at 15–30 m/min for 35 min. Immediately after exercise, the blood, skeletal muscles, adipose, heart, and liver were collected; the levels of FSTL1 and apelin were measured. Results: Serum FSTL1 and apelin were significantly increased following acute exercise; in contrast, the levels of FSTL1 and apelin in the tissues were not affected. Conclusions: Acute endurance exercise may stimulate the secretion of FSTL1 and apelin into the circulation, however, the origin of their increased secreted levels may not be the metabolic organs.