Construction of a luminescent eleven-metal Zn(ii)–Tb(iii) nanocluster for rapid and quantitative time-gated detection of guanosine-5-monophosphate and RNA. Issue 37 (3rd September 2022)

• Record Type: Journal Article
• Authors: Zhu, Ting; Chen, Ya; Yang, Xiaoping; Leng, Xilong; Schipper, Desmond
• Is Part Of: CrystEngComm. Volume 24:Issue 37(2022)
• Page Start: 6527
• Page End: 6533
• Publication Date: 2022-09-03
• Subjects: Crystals -- Periodicals; Crystal growth -- Periodicals; Crystallography -- Periodicals; Cristaux -- Périodiques; Cristaux -- Croissance -- Périodiques; Cristallographie -- Périodiques; 548
• DOI: 10.1039/d2ce00753c
• Languages: English
• ISSNs: 1466-8033

Abstract

Abstract : An eleven-metal Zn(ii )–Tb(iii ) nanocluster with a Schiff base ligand was constructed as a luminescent probe for quantitative time-gated detection of guanosine-5-monophosphate and RNA. Abstract : One 11-metal Zn(ii )–Tb(iii ) nanocluster 1 was synthesized using a tetradentate Schiff base ligand. The addition of GMP and RNA results in the enhancement of Tb(iii ) luminescence of 1, which is dominated by a static model. 1 exhibits highly sensitive TRL detection of GMP and RNA with a delay time of 300 μs, and the corresponding linear fitting equations are ( I – I 0 )/ I 0 = 10.34· C GMP − 223.42 and ( I – I 0 )/ I 0 = 6.06· C RNA − 7.47 with correlation coefficients R 2 = 0.9513 and 0.9909, respectively. The limits of detection for GMP and RNA are 3.11 μM and 0.53 ng μL −1, respectively, and 1 can be used to determine the concentrations of GMP and RNA accurately. 1 displays a rapid and stable luminescence response to the analytes, with response times less than ten seconds and no changes for the lanthanide emission in one week.