Pathophysiology and aetiology of hypoglycaemic crises. (13th August 2018)

• Record Type: Journal Article
• Authors: Morgan, R. K.; Cortes, Y.; Murphy, L.
• Is Part Of: Journal of small animal practice. Volume 59:Number 11(2018)
• Page Start: 659
• Page End: 669
• Publication Date: 2018-08-13
• Subjects: Veterinary medicine -- Periodicals; Veterinary Medicine -- Periodicals; 636.089
• DOI: 10.1111/jsap.12911
• Languages: English
• ISSNs: 0022-4510

Abstract

Abstract : Hypoglycaemia is a common, life‐threatening complication that occurs as a component of a wide variety of disease processes. Despite its frequent occurrence, information concerning the aetiology, characteristics and outcomes of hypoglycaemic crises in veterinary medicine is limited. This review summarises the current understanding of the pathophysiology of hypoglycaemia, the body's counter‐regulatory response, underlying aetiologies, diagnosis and treatment. Disease mechanisms are discussed and published evidence in veterinary literature regarding prognostic indicators, prevalence, diagnosis and treatment is examined for hypoglycaemia‐related disease processes including insulinoma, glucose‐lowering toxins and medications.