Outpacing the resistance tsunami: Antimicrobial stewardship in equine medicine, an overview. (24th June 2020)

• Record Type: Journal Article
• Authors: Prescott, J. F.
• Is Part Of: Equine veterinary education. Volume 33:Number 10(2021)
• Page Start: 539
• Page End: 545
• Publication Date: 2020-06-24
• Subjects: horse -- antimicrobial stewardship -- antimicrobial resistance -- equine medicine -- major elements -- editorial; Horses -- Diseases -- Periodicals; Horses -- Diseases -- Treatment -- Periodicals; 636.108905
• DOI: 10.1111/eve.13318
• Languages: English
• ISSNs: 0957-7734

Abstract

Summary: Antimicrobial stewardship (AMS) is the term increasingly used to describe the multiple approaches needed to sustain the efficacy of antimicrobial drugs in the face of the increasing development and spread of antimicrobial resistance in bacterial pathogens, and the global crisis in medicine that it is engendering. The concept and the practices associated with AMS continue to evolve but the general approach is a dynamic and multifaceted one of continuous improvement based on reducing, improving, monitoring and evaluating the use of antimicrobials so as to preserve their future efficacy and to protect human and animal health. Using many equine examples, this basic overview discusses the multiple and interacting elements of AMS: Practice guidelines, infection control and prevention, clinical microbiology, resistance and use surveillance, dosage, pharmacokinetics and pharmacodynamics, regulation, education and owner compliance, leadership, coordination and measurement. There have been impressive advances in recent years in reporting and analysis of AMR in horses, in the scrutiny and assessment of how antimicrobial drugs are used in horses and in identification of areas for improvement including dosing, surgical prophylaxis, infection control, development of practice standards and the use of clinical microbiology. Antimicrobial stewardship is taking shape as we start to see the emergence of evidence‐based recommendations but far more is required. Containing and even rolling back AMR will need the continued engagement of practitioners, equine national and international practitioner organisations, researchers and educators in the academic community, horse owners, regulators and others.