Improved production of 68Ga-Pentixafor using cartridge mediated cation exchange purification. (November 2022)

• Record Type: Journal Article
• Authors: Nader, M.; Herrmann, K.; Kunkel, F.; Zarrad, F.; Pacelli, A.; Fendler, W.; Koplin, S.
• Is Part Of: Applied radiation and isotopes. Volume 189(2022)
• Publication Date: 2022-11
• Subjects: Radiology -- Periodicals; Radiation -- Industrial applications -- Periodicals; Nuclear chemistry -- Periodicals; Internet resource; Periodical; 660.298
• DOI: 10.1016/j.apradiso.2022.110447
• Languages: English
• ISSNs: 0969-8043

Abstract

Highlights: Streamlined automated production of [ 68 Ga]Ga-pentixafor. Increased [ 68 Ga]Ga-pentixafor yield by application of a Multi Generator Tool. Reduced synthesis time of 14, 5 min. Significant reduction of ethanol content (3, 5 ± 0.5 mg/mL).