Management of optic disc pit maculopathy: the European VitreoRetinal society optic pit study. Issue 6 (7th December 2021)

• Record Type: Journal Article
• Authors: Iros, Mariano; Parolini, Barbara; Ozdek, Sengul; Gini, Giampaolo; Nawrocka, Zofia Anna; Ellabban, Abdallah A; Faramawi, Mohammed F.; Adelman, Ron; Sallam, Ahmed B.
• Other Names: Meireles Angelina investigator.; Lee Christopher Seungkyu investigator.; Ducournau Didier investigator.; Tsouris Dimitros investigator.; Kozina Elena investigator.; Patelli Fabio investigator.; Viola Francesco investigator.; Ascaso Francisco investigator.; Becquet Frank investigator.; Tosi Gian Marco investigator.; Besozzi Gianluca investigator.; Oh Hideyasu investigator.; Othman Ihab Saad investigator.; Fiser Ivan investigator.; Le Rouic Jean‐François investigator.; Perone Jean‐Marc investigator.; Amar Jean‐Paul investigator.; Nawrocki Jerzy investigator.; Nascimento Joao investigator.; Arrevola Luis investigator.; Nagpal Manish investigator.; Mehrotra Navneet investigator.; Demir Mehmet investigator.; Chelazzi Paolo investigator.; Miesbauer Peter investigator.; Turkcuoglu Peykan investigator.; Koch Philippe investigator.; Uy Robert investigator.; Weinfurter Sandra B. investigator.; Bopp Silvia investigator.; Park SuzannS investigator.; Schönherr Ulrich investigator.; Alsanova Veronika investigator.; Bonfiglio Vicenza investigator.; Szijárt Zsuzsanna investigator.;
• Is Part Of: Acta ophthalmologica. Volume 100:Issue 6(2022)
• Page Start: e1264
• Page End: e1271
• Publication Date: 2021-12-07
• Subjects: gas tamponade -- internal limiting membrane peeling -- optic disc pit maculopathy -- optic nerve pit maculopathy -- pars plana vitrectomy -- retreatment; Ophthalmology -- Periodicals; 617.7005
• DOI: 10.1111/aos.15076
• Languages: English
• ISSNs: 1755-375X

Abstract

Abstract: Purpose: To evaluate a variety of techniques, and their anatomical and functional results, for the treatment of optic disc pit maculopathy (ODP‐M). A secondary aim was to report on results of secondary procedures in cases of initial failure or recurrence. Methods: Multicentre retrospective study of 95 eyes with ODP‐M, treated by 25 surgeons from 12 countries. Primary outcomes were anatomical resolution of subretinal fluid (SRF), intraretinal fluid (IRF) and visual acuity (VA) at 12 months. Results: Higher rates of SRF and IRF resorption were achieved in eyes treated with pars plana vitrectomy (PPV) compared to external laser with or without tamponade: 64/72 (88.9%) versus 8/14 (57.1%) for SRF (p = 0.003), and 50/59 (84.7%) versus 3/10 (30%) for IRF (p = 0.002). The addition of juxtapapillary laser or internal limiting membrane (ILM) peel during PPV did not improve SRF or IRF resolution. Pars plana vitrectomy (PPV) with tamponade and PPV with tamponade plus endolaser were associated with significant visual gain. In the former group, VA improved from a mean of logMAR 0.91 (20/162), to a mean of logMAR 0.52 (20/66) at 12 months; in the latter group, VA improved from a mean of logMAR 0.82 (20/132) to a mean of logMAR 0.47 (20/59) at 12 months. Retreatments were performed in 14 eyes (15.7%), only enhancing anatomical outcomes. Conclusion: Vitrectomy with tamponade had better final outcomes than external laser treatment with or without gas tamponade. Laser endophotocoagulation and ILM peel provided no additional benefit. A secondary treatment resulted in anatomical but not functional improvement.