Shielding Surfaces from Viruses and Bacteria with a Multiscale Coating. Issue 23 (3rd June 2022)

• Record Type: Journal Article
• Authors: Ashok, Deepu; Taheri, Mahdiar; Garg, Puneet; Webb, Daryl; Parajuli, Pawan; Wang, Yi; Funnell, Bronte; Taylor, Bradley; Tscharke, David C.; Tsuzuki, Takuya; Verma, Naresh K.; Tricoli, Antonio; Nisbet, David R.
• Is Part Of: Advanced science. Volume 9:Issue 23(2022)
• Page Start: n/a
• Page End: n/a
• Publication Date: 2022-06-03
• Subjects: antibacterial -- antiviral -- multiscale coatings -- infections -- ZIF‐8 metal–organic frameworks (MOFs); Science -- Periodicals; 505
• DOI: 10.1002/advs.202201415
• Languages: English
• ISSNs: 2198-3844

Abstract

Abstract: The spread of viral and bacterial pathogens mediated by contact with surfaces is a leading cause of infection worldwide. COVID‐19 and the continuous rise of deaths associated with antibiotic‐resistant bacteria highlight the need to impede surface‐mediated transmission. A sprayable coating with an intrinsic ability to resist the uptake of bacteria and viruses from surfaces and droplets, such as those generated by sneezing or coughing, is reported. The coating also provides an effective microbicidal functionality against bacteria, providing a dual barrier against pathogen uptake and transmission. This antimicrobial functionality is fully preserved following scratching and other induced damage to its surface or 9 days of submersion in a highly concentrated suspension of bacteria. The coatings also register an 11‐fold decrease in viral contamination compared to the noncoated surfaces. Abstract : The development of a ZIF‐8 metal–organic framework‐hierarchical dual functional coating with durable properties that can resist pathogen adhesion is reported. The coating is mechanistically characterized for both antiviral and antibacterial properties, registering excellent performance in reducing the surface residence time of viruses and resisting formation of biofilms by bacteria.