Grafting polymer brushes by ATRP from functionalized poly(ether ether ketone) microparticles. (1st June 2021)

• Record Type: Journal Article
• Authors: Fu, Liye; Jafari, Hossein; Gießl, Michael; Yerneni, Saigopalakrishna S.; Sun, Mingkang; Wang, Zongyu; Liu, Tong; Kapil, Kriti; Cheng, Boyle C.; Yu, Alexander; Averick, Saadyah E.; Matyjaszewski, Krzysztof
• Other Names: Penczek Stanislaw guestEditor.; Matyjaszewski Krzysztof guestEditor.
• Is Part Of: Polymers for advanced technologies. Volume 32:Number 10(2021)
• Page Start: 3948
• Page End: 3954
• Publication Date: 2021-06-01
• Subjects: ATRP -- brushes -- PEEK; Polymers -- Periodicals; 668.9
• DOI: 10.1002/pat.5405
• Languages: English
• ISSNs: 1042-7147

Abstract

Abstract: Poly(ether ether ketone) (PEEK) is a semi‐crystalline thermoplastic with excellent mechanical and chemical properties. PEEK exhibits a high degree of resistance to thermal, chemical, and bio‐degradation. PEEK is used as a biomaterial in the field of orthopedic and dental implants; however, due to its intrinsic hydrophobicity and inert surface, PEEK does not effectively support bone growth. Therefore, new methods to modify PEEK's surface to improve osseointegration are key to next‐generation polymer implant materials. Unfortunately, PEEK is a challenging material to both modify and subsequently characterize thus stymieing efforts to improve PEEK osseointegration. In this manuscript, we demonstrate how surface‐initiated atom transfer radical polymerization can be used to modify novel PEEK microparticles (PMP). The hard core‐soft shell microparticles were synthesized and characterized by dynamic light scattering, attenuated total reflection‐infrared, X‐ray photoelectron spectroscopy, and transmission electron microscopy, indicating the grafted materials increased solubility and stability in a range of solvents. The discovered surface grafted PMP can be used as compatibilizers for the polymer‐tissue interface.