Dependence of laser‐induced optical breakdown on skin type during 1064 nm picosecond laser treatment. Issue 9 (18th June 2021)

• Record Type: Journal Article
• Authors: Kim, Hyeonsoo; Hwang, Jewan Kaiser; Choi, Jongman; Kang, Hyun Wook
• Is Part Of: Journal of biophotonics. Volume 14:Issue 9(2021)
• Page Start: n/a
• Page End: n/a
• Publication Date: 2021-06-18
• Subjects: diffractive optical elements -- fitzpatrick skin type -- laser‐induced optical breakdown -- micro‐lens arrays -- picosecond laser skin treatment; Photonics -- Periodicals; Optical materials -- Periodicals; Optics -- Periodicals; Medical instruments and apparatus -- Periodicals; 621.3605
• DOI: 10.1002/jbio.202100129
• Languages: English
• ISSNs: 1864-063X

Abstract

Abstract: The current study aims to evaluate the dependence of laser‐induced optical breakdown (LIOB) on skin types by using 1064 nm picosecond laser with micro‐lens arrays (MLA) and diffractive optical elements (DOE). Both black and white skin tissues were examined to comparatively assess the LIOB effects in the skin in terms of laser‐induced vacuolization. The black skin irradiated at 3.0 J/cm 2 demonstrated that MLA yielded a deeper distribution (180‐400 μm) of laser‐induced vacuoles with a size of 67 μm, compared to DOE (180‐280 μm; 40 μm in size). However, the white skin presented that MLA created larger vacuoles (134 μm in size) in a smaller number at deeper distributions (125‐700 μm) than MLA with the black skin. DOE generated no laser‐induced vacuolization in the white skin. The white skin tissue with inherent higher scattering could be responsible for deeper vacuolization after the picosecond laser treatment. Further investigations are expected to determine the optimal treatment conditions for various skin types. Abstract : Laser treatment is commonly used for melasma in the clinical field. Treatment outcomes are highly dependent on the optical properties of skin types. The current study evaluates the dependence of laser‐induced optical breakdown effects on two different porcine skin types. Histology results revealed a deeper and larger distribution of laser‐induced vacuolization for white skin tissue, compared to black skin tissue.