Functional network activity during errorless and trial‐and‐error color‐name association learning. Issue 8 (18th June 2020)

• Record Type: Journal Article
• Authors: Yamashita, Madoka; Shimokawa, Tetsuya; Peper, Ferdinand; Tanemura, Rumi
• Is Part Of: Brain and behavior. Volume 10:Issue 8(2020)
• Page Start: n/a
• Page End: n/a
• Publication Date: 2020-06-18
• Subjects: cognitive function -- fMRI -- learning -- rehabilitation; Neurology -- Periodicals; Neurosciences -- Periodicals; Psychology -- Periodicals; Psychiatry -- Periodicals; 616.8005
• DOI: 10.1002/brb3.1723
• Languages: English
• ISSNs: 2162-3279

Abstract

Abstract: Introduction: In cognitive rehabilitation, errorless (EL) and trial‐and‐error (T&E) learning are well‐known methods, but their neural mechanisms are not well known. In this study, we investigated functional magnetic resonance imaging data for healthy adults during EL and T&E learning. Methods: Participants memorized color‐name associations in both methods using Japanese traditional colors which were unfamiliar to study participants. A functional network analysis was conducted by applying graph theory. We focused on two major cognitive networks: the default mode network (DMN) and the fronto‐parietal network (FPN). Also, we used "within‐network connectivity" and "between‐network connectivity" graph metrics. The former represents the functional connectivity strength of a subnetwork, namely the within‐DMN connectivity and within‐FPN connectivity, while the latter represents the number of links between the DMN and FPN. Results: The within‐DMN connectivity in T&E learning was significantly higher than in EL learning. The difference between the memory scores of EL and T&E learning weakly correlated with the between‐network connectivity differences between both learning tasks. Conclusions: Our results suggest that within‐DMN connectivity is important in T&E learning and that the learning benefit differences between EL and T&E approaches potentially relate to the functional integration strength between the DMN and FPN. Abstract : Participants memorised colour‐name associations in errorless(EL) and trial‐and‐error(T&E) methods using Japanese traditional colours which were unfamiliar to study participants. We focused on the default mode network (DMN) and the fronto‐parietal network (FPN), and conducted functional network analysis by applying graph theory. Our results suggest that within‐DMN connectivity is important in T&E learning and that the learning benefit differences between EL and T&E approaches possibly relate to the functional integration strength between the DMN and FPN.