Lactate dehydrogenase in dermatology practice. (21st November 2019)

• Record Type: Journal Article
• Authors: Livesey, A.; Garty, F.; Shipman, A. R.; Shipman, K. E.
• Is Part Of: Clinical and experimental dermatology. Volume 45:Number 5(2020)
• Page Start: 539
• Page End: 543
• Publication Date: 2019-11-21
• Subjects: Skin -- Diseases -- Periodicals; 616.5
• DOI: 10.1111/ced.14134
• Languages: English
• ISSNs: 0307-6938

Abstract

Summary: Lactate dehydrogenase (LDH) is used in dermatology practice, particularly as a prognostic marker for cutaneous lymphoma. LDH is an intracellular enzyme involved in anaerobic glycolysis, and is found at low concentrations in the blood. LDH is produced in every tissue, thus cell damage releases LDH into the circulation, so the causes of elevated LDH levels are multiple. The utility of LDH in dermatology practice is reviewed, alongside current diagnostic and staging guidelines. Abstract : Click here for the corresponding questions to this CME article.