Flows and function of the Infant Flow neonatal continuous positive airway pressure device investigated with computational fluid dynamics. (19th August 2020)

• Record Type: Journal Article
• Authors: Drevhammar, Thomas; Berg, Niclas; Nilsson, Kjell; Jonsson, Baldvin; Prahl Wittberg, Lisa
• Is Part Of: Acta pædiatrica. Volume 110:Number 3(2021)
• Page Start: 811
• Page End: 817
• Publication Date: 2020-08-19
• Subjects: continuous positive airway pressure -- computational fluid dynamics -- equipment design -- infant premature; Pediatrics -- Periodicals; Pediatrics; 618.92
• DOI: 10.1111/apa.15502
• Languages: English
• ISSNs: 0803-5253

Abstract

Abstract: Aim: The first dedicated neonatal continuous positive airway pressure (CPAP) device using variable flow was the Infant Flow. The system was pressure stable with a low resistance to breathing. The aim of this study was to describe the flow and function of the Infant Flow geometry using simulated breathing and computational fluid dynamics. Method: The original Infant Flow geometry was used with simulated term infant breathing at three levels of CPAP. The large eddy simulation methodology was applied in combination with the WALE sub‐grid scale model. Results: The simulation fully resolved the flow phenomena in the Infant Flow geometry. The main flow feature during inspiration was support by gas entrainment and mixing. During expiration, the jet deflected towards the outlet with unstable impingement of the jet at the opposing edge. Conclusion: The proposed mechanism has previously been based on theoretical reasoning, and our results present the first detailed description of the Infant Flow. The pressure stability was based on a jet supporting inspiration by gas entrainment and then being deflected during exhalation. This confirmed previously assumed principles of function and flows within the geometry and provided a base for further developments.