Guidance on allergenicity assessment of genetically modified plants. (22nd June 2017)

• Record Type: Journal Article
• Authors: Naegeli, Hanspeter; Birch, Andrew Nicholas; Casacuberta, Josep; De Schrijver, Adinda; Gralak, Mikolaj Antoni; Guerche, Philippe; Jones, Huw; Manachini, Barbara; Messéan, Antoine; Nielsen, Elsa Ebbesen; Nogué, Fabien; Robaglia, Christophe; Rostoks, Nils; Sweet, Jeremy; Tebbe, Christoph; Visioli, Francesco; Wal, Jean‐Michel; Eigenmann, Philippe; Epstein, Michelle; Hoffmann‐Sommergruber, Karin; Koning, Frits; Lovik, Martinus; Mills, Clare; Moreno, Francisco Javier; van Loveren, Henk; Selb, Regina; Fernandez Dumont, Antonio
• Is Part Of: EFSA journal. Volume 15:Number 6(2017)
• Page Start: n/a
• Page End: n/a
• Publication Date: 2017-06-22
• Subjects: guidance -- allergenicity assessment -- newly expressed proteins -- endogenous allergenicity -- GMO; Food -- Europe -- Safety measures -- Periodicals; Food Safety; Food -- Safety measures; Europe; Periodicals; Periodicals; Fulltext; Government Publications, International; Internet Resources; Periodicals; Periodicals; 363.19209405
• DOI: 10.2903/j.efsa.2017.4862
• Languages: English
• ISSNs: 1831-4732

Abstract

Abstract: This document provides supplementary guidance on specific topics for the allergenicity risk assessment of genetically modified plants. In particular, it supplements general recommendations outlined in previous EFSA GMO Panel guidelines and Implementing Regulation (EU) No 503/2013. The topics addressed are non‐IgE‐mediated adverse immune reactions to foods, in vitro protein digestibility tests and endogenous allergenicity. New scientific and regulatory developments regarding these three topics are described in this document. Considerations on the practical implementation of those developments in the risk assessment of genetically modified plants are discussed and recommended, where appropriate. Abstract : This publication is linked to the following EFSA Supporting Publications article: http://onlinelibrary.wiley.com/doi/10.2903/sp.efsa.2017.EN-1259/full