Non-neoplastic colorectal disease biopsies: evaluation and differential diagnosis. Issue 12 (31st July 2020)

• Record Type: Journal Article
• Authors: Moore, Michelle; Feakins, Roger M; Lauwers, Gregory Y
• Is Part Of: Journal of clinical pathology. Volume 73:Issue 12(2020)
• Page Start: 783
• Page End: 792
• Publication Date: 2020-07-31
• Subjects: colon -- colitis -- inflammatory bowel diseases; Pathology -- Periodicals; Pathology, Molecular -- Periodicals; 616.0705
• DOI: 10.1136/jclinpath-2020-206794
• Languages: English
• ISSNs: 0021-9746

Abstract

Abstract : A wide variety of non-neoplastic conditions may be encountered on colorectal biopsy encompassing idiopathic, infectious, vascular and immune-mediated aetiologies. Although interpretation of such biopsies may be challenging, appreciation of the dominant pattern of injury and subsequent host response may allow for a more focused histological diagnosis in the correct clinical and endoscopic setting. This article aims to provide a systematic, methodical approach to the assessment of such biopsies, concentrating mainly on diagnoses other than inflammatory bowel disease.