Surveillance arterioveNous fistulAs using ultRasound (SONAR) trial in haemodialysis patients: a study protocol for a multicentre observational study. Issue 7 (23rd July 2019)

• Record Type: Journal Article
• Authors: Richards, James; Hossain, Mohammed; Summers, Dominic; Slater, Matthew; Bartlett, Matthew; Kosmoliaptsis, Vasilis; Wilson, Edward CF; Lagaac, Regin; Sidders, Anna; Foley, Claire; Laing, Emma; Hopkins, Valerie; Fitzpatrick-Creamer, Chloe; Hudson, Cara; Thomas, Helen; Turner, Sam; Tambyraja, Andrew; Somalanka, Subash; Hunter, James; Dutta, Sam; Lawman, Sarah; Salter, Tracey; Aslam, Mohammed; Bagul, Atul; Sivaprakasam, Rajesh; Smith, George; Moinuddin, Zia; Knight, Simon; Gibbs, Paul; Motallebzadeh, Reza; Barnett, Nicholas; Pettigrew, Gavin;
• Other Names: author non-byline.; Deary Alison author non-byline.; Surendrakumar Veena author non-byline.; Ayorinde Tobi author non-byline.; Chipurovski Igor author non-byline.; Paul Subhankar author non-byline.; Bond Klaus author non-byline.; Hardy Elizabeth author non-byline.; Widdup Joanne author non-byline.; Potter Rachael author non-byline.; Pugh Elisabeth author non-byline.; Parsons Karen author non-byline.; Lafferty Kathryn author non-byline.; Sivaprakasam Rajesh author non-byline.; Crawford Kate author non-byline.; Bolsworth Amy author non-byline.; Ngwa-Ndifor Naavalah author non-byline.; Badhan Rani author non-byline.; Edlin Helena author non-byline.; Jerram Anna author non-byline.; Lai Jessica author non-byline.; Banda Joyce author non-byline.; Bendle Janet author non-byline.; Turner Sam author non-byline.; Morgan Maria author non-byline.; Owen William author non-byline.; Dawson Sue author non-byline.; Daniel Simon author non-byline.; Allsop Karen author non-byline.; Carmichael Sarah-Jane author non-byline.; Eadie Tom author non-byline.; Lochiel Rona author non-byline.; Lena Midel author non-byline.; Padayachee Soundrie author non-byline.; Eldridge Philip author non-byline.; Rabuya May author non-byline.; Patel Jashree author non-byline.; Ghazanfar Abbas author non-byline.; Selm Judy Van author non-byline.; Bodneck Caroline author non-byline.; Augustin Martia author non-byline.; Ansu Kwame author non-byline.; Khosla Nalin author non-byline.; Burney Kashif author non-byline.; Dear Karen author non-byline.; Tiivas Carl author non-byline.; Hyndman Samantha author non-byline.; Truslove Maria author non-byline.; Beech Andrew author non-byline.; Brand Sarah author non-byline.; Cheal Darren author non-byline.; Smith Mel author non-byline.; Trivedi Kate author non-byline.; Bajwa Adnan author non-byline.; Kerr John author non-byline.; Fleet Ana author non-byline.; Chapman Lianne author non-byline.; Gee Sarah author non-byline.; Weerasinghe Thanuja author non-byline.; Cai Paris author non-byline.; Long Judith author non-byline.; Rowe Tracey author non-byline.; Crane Jeremy author non-byline.; Quashie-Akponeware Mary author non-byline.;
• Is Part Of: BMJ open. Volume 9:Issue 7(2019)
• Publication Date: 2019-07-23
• Subjects: end stage renal failure -- dialysis -- surgery -- ultrasound; Medicine -- Research -- Periodicals; 610.72
• DOI: 10.1136/bmjopen-2019-031210
• Languages: English
• ISSNs: 2044-6055

Abstract

Abstract : Introduction: Arteriovenous fistulas (AVFs) are considered the best and safest modality for providing haemodialysis in patients with end-stage renal disease. Only 20% of UK centres achieve the recommended 80% target for achieving dialysis of the prevalent dialysis population via permanent access (as opposed to a central venous catheter). This is partly due to the relatively poor maturation rate of newly created fistulas, with as many as 50% of fistulas failing to mature. The Surveillance Of arterioveNous fistulAe using ultRasound study will examine whether a protocolised programme of Doppler ultrasound (US) surveillance can identify, early after creation, potentially correctable problems in those AVFs that subsequently fail to mature. Methods and analysis: This is a multicentre observational study that will assess newly created AVFs by Doppler US performed at 2, 4, 6 and 10 weeks after creation. The primary outcome measure will be primary fistula patency at week 10. Secondary outcome measures include: successful use of the fistula; clinical suitability for dialysis; creation of new fistula or radiological salvage; fistula thrombosis; secondary fistula patency rate and patient acceptability. Ethics and dissemination: The study has been approved by the Cambridgeshire and Hertfordshire Research Ethics Committee and by the Health Research Authority (REC 18/EE/0234). The results generated from this work will be published as open access, within 3 years of trial commencement. We will also present our findings at key national/international renal meetings, as well as support volunteers at renal patient groups to disseminate the trial outcome. Trial registration number: ISRCTN36033877