Local T cell subsets in mumps meningitis. Issue 11 (November 1983)

• Record Type: Journal Article
• Authors: Nagai, H; Morishima, T; Morishima, Y; Isomura, S; Suzuki, S
• Is Part Of: Archives of disease in childhood. Volume 58:Issue 11(1983)
• Page Start: 927
• Page End: 928
• Publication Date: 1983-11
• Subjects: Children -- Diseases -- Periodicals; Infants -- Diseases -- Periodicals; 618.920005
• DOI: 10.1136/adc.58.11.927
• Languages: English
• ISSNs: 0003-9888

Abstract

Abstract : In the acute phase of mumps meningitis, more than 85% of the cells in cerebrospinal fluid (CSF) were OKT 3 positive, while 76% of the peripheral mononuclear cells (PMN) were OKT 3 positive. The ratio of OKT 4:8 positive cells in CSF was significantly lower than that in PMN, showing that suppressor/cytotoxic T cells had selectively accumulated in CSF. In addition, 58% of CSF cells were immune associated (Ia) positive, probably activated T cells.