Brucellosis with nephrotic syndrome, nephritis and IgA nephropathy. Issue 804 (October 1992)

• Record Type: Journal Article
• Authors: Siegelmann, N.; Abraham, A. S.; Rudensky, B.; Shemesh, O.
• Is Part Of: Postgraduate medical journal. Volume 68:Issue 804(1992)
• Page Start: 834
• Page End: 836
• Publication Date: 1992-10
• Subjects: Medicine -- Periodicals; 610
• DOI: 10.1136/pgmj.68.804.834
• Languages: English
• ISSNs: 0032-5473

Abstract

Abstract : A patient with systemic brucellosis due to Brucella melitensis had severe renal involvement. Clinical features included hypertension, macroscopic haematuria, massive proteinuria of 10 g per 24 hours and azotaemia. Following treatment with antibiotics, the azotaemia resolved and proteinuria decreased to less than 0.5 g per 24 hours, but microscopic haematuria and hypertension persisted. Renal biopsy during recovery revealed IgA nephropathy with minimal mesangial changes, suggesting a causal relation between brucellosis and IgA nephropathy with a reversible nephrotic syndrome.