Injectable Microfluidic Hydrogel Microspheres for Cell and Drug Delivery. (13th May 2021)

• Record Type: Journal Article
• Authors: Zhao, Zhenyu; Wang, Zhen; Li, Gen; Cai, Zhengwei; Wu, Jiezhou; Wang, Lei; Deng, Lianfu; Cai, Ming; Cui, Wenguo
• Is Part Of: Advanced functional materials. Volume 31:Number 31(2021)
• Page Start: n/a
• Page End: n/a
• Publication Date: 2021-05-13
• Subjects: biomaterials -- cell delivery -- drug delivery -- hydrogel microspheres -- microfluidics; Materials -- Periodicals; Chemical vapor deposition -- Periodicals; 620.11
• DOI: 10.1002/adfm.202103339
• Languages: English
• ISSNs: 1616-301X

Abstract

Abstract: Microfluidic hydrogel microspheres have been broadly studied across a wide range of industries and applications, and their use in the medical field, including control cells and drug delivery, is increasing. The usual design of these materials is intended to enable the efficient and smart encapsulation of cells and/or drugs in microspheres in which the functionalities and features are effectively controlled, lending itself some unique properties. These characteristics promote exchanges and cooperation in multiple disciplines and boost the development of precision medicine, new manufacturing technologies, and applied materials. This review begins with a discussion of microfluidic hydrogel microspheres and then introduces the preparation equipment, main principles, and related characteristics of the microspheres. Furthermore, the medical applications of microfluidic hydrogel microspheres for delivering cells and drugs are emphasized. Finally, this review discusses perspectives and future directions for accelerating the development and application of microfluidic hydrogel microspheres for controlled delivery. Abstract : This review begins with a discussion of microfluidic hydrogel microspheres, and then introduces the preparation equipment, main principles, and related characteristics of the microspheres. Furthermore, the medical applications of microfluidic hydrogel microspheres for delivering cells and drugs are emphasized. Finally, the review discusses perspectives and future directions for accelerating the development and application of microfluidic hydrogel microspheres in controlled delivery.