Asymmetric total synthesis of (+)-isocryptotanshinone and formal synthesis of (−)-cryptotanshinone. Issue 30 (26th July 2019)
- Record Type:
- Journal Article
- Title:
- Asymmetric total synthesis of (+)-isocryptotanshinone and formal synthesis of (−)-cryptotanshinone. Issue 30 (26th July 2019)
- Main Title:
- Asymmetric total synthesis of (+)-isocryptotanshinone and formal synthesis of (−)-cryptotanshinone
- Authors:
- Shi, Xiang
Liu, Xiaoyu
Yang, Feilong
Wang, Yong
Wang, Zhenwei
Jiao, Xiaozhen
Xie, Ping - Abstract:
- Abstract: The first asymmetric total synthesis of (+)-isocryptotanshinone was achieved in 12 linear steps with 12% overall yield from commercially available dihydrobenzopyrone. The key step was a base-mediated cyclization reaction. In addition, the synthetic strategy included the formal synthesis of (−)-cryptotanshinone. Graphical abstract: Image 1
- Is Part Of:
- Tetrahedron. Volume 75:Issue 30(2019)
- Journal:
- Tetrahedron
- Issue:
- Volume 75:Issue 30(2019)
- Issue Display:
- Volume 75, Issue 30 (2019)
- Year:
- 2019
- Volume:
- 75
- Issue:
- 30
- Issue Sort Value:
- 2019-0075-0030-0000
- Page Start:
- 3962
- Page End:
- 3967
- Publication Date:
- 2019-07-26
- Subjects:
- (+)-isocryptotanshinone -- Asymmetric total synthesis -- (−)-Cryptotanshinone -- STAT3 inhibitor -- Base-mediated cyclization
Chemistry, Organic -- Periodicals
547.005 - Journal URLs:
- http://www.elsevier.com/journals ↗
- DOI:
- 10.1016/j.tet.2019.05.069 ↗
- Languages:
- English
- ISSNs:
- 0040-4020
- Deposit Type:
- Legaldeposit
- View Content:
- Available online (eLD content is only available in our Reading Rooms) ↗
- Physical Locations:
- British Library DSC - 8796.850000
British Library DSC - BLDSS-3PM
British Library STI - ELD Digital store - Ingest File:
- 23755.xml