Persistence of chlamydial infection after treatment for neonatal conjunctivitis. Issue 3 (March 1981)

• Record Type: Journal Article
• Authors: Rees, E; Tait, I A; Hobson, D; Karayiannis, P; Lee, N
• Is Part Of: Archives of disease in childhood. Volume 56:Issue 3(1981)
• Page Start: 193
• Page End: 198
• Publication Date: 1981-03
• Subjects: Children -- Diseases -- Periodicals; Infants -- Diseases -- Periodicals; 618.920005
• DOI: 10.1136/adc.56.3.193
• Languages: English
• ISSNs: 0003-9888

Abstract

Abstract : A high incidence of pharyngeal infection was found in babies with isolation-positive chlamydial conjunctivitis. Chlamydia trachomatis was isolated from the pharynx of 12 (52%) of 23 babies before treatment, and was reisolated from the eyes of 4 (12%) of 34 and from the pharynx of 14 (41%) of 34 after treatment. C trachomatis was reisolated significantly more often from babies treated only with topical tetracycline for 4 weeks (75%) than from those treated with both topical tetracycline and oral erythromycin for 2 weeks (32%). Reisolation from the eyes was associated with only minor clinical signs. Radiological signs of an inflammatory lesion in the chest were found in 2 of 8 babies examined because of persistent cough. These signs were not associated with high or rising titres of serum chlamydial antibody.