Progressive hypogammaglobulinaemia in a child born to a mother with Hodgkin's disease. Issue 4 (April 1979)

• Record Type: Journal Article
• Authors: Evans, D I; Burn, J L
• Is Part Of: Archives of disease in childhood. Volume 54:Issue 4(1979)
• Page Start: 313
• Page End: 315
• Publication Date: 1979-04
• Subjects: Children -- Diseases -- Periodicals; Infants -- Diseases -- Periodicals; 618.920005
• DOI: 10.1136/adc.54.4.313
• Languages: English
• ISSNs: 0003-9888

Abstract

Abstract : A young woman developed Hodgkin's disease (nodular sclerosis) in pregnancy and gave birth to a boy who developed common variable immunodeficiency. Initially there was normal IgG with low IgA and IgM, and antibody deficiency. IgG levels fell progressively over 4 years. Cellular immunity was normal. We suggest that this is a further family with immune deficiency presenting with common variable immunodeficiency and lymphoid malignancy.