Influence of pH on the efficacy of pilocarpine. Issue 5 (May 1978)

• Record Type: Journal Article
• Authors: David, R; Goldberg, L; Luntz, M H
• Is Part Of: British journal of ophthalmology. Volume 62:Issue 5(1978)
• Page Start: 318
• Page End: 319
• Publication Date: 1978-05
• Subjects: Ophthalmology -- Periodicals; 617.7
• DOI: 10.1136/bjo.62.5.318
• Languages: English
• ISSNs: 0007-1161

Abstract

Abstract : Pilocarpine 4% solutions at pH 4.1 and 5.8 were compared in a double-blind clinical trial on 24 eyes of patients with primary open-angle glaucoma. Each drug was used over a period of 1 week. No significant difference in the lowering of intraocular pressure was found, and the near-neutral solution of pilocarpine was found to be equally stable when compared to the acid solution over a 6-month period.