Hereditary coproporphyria and epilepsy. Issue 8 (August 1977)

• Record Type: Journal Article
• Authors: Houston, A B; Brodie, M J; Moore, M R; Thompson, G G; Stephenson, J B
• Is Part Of: Archives of disease in childhood. Volume 52:Issue 8(1977)
• Page Start: 646
• Page End: 650
• Publication Date: 1977-08
• Subjects: Children -- Diseases -- Periodicals; Infants -- Diseases -- Periodicals; 618.920005
• DOI: 10.1136/adc.52.8.646
• Languages: English
• ISSNs: 0003-9888

Abstract

Abstract : A 9-year-old boy with mental deterioration and epilepsy suffered an acute attack of hereditary coproporphyria associated with worsening of seizure control. Leucocyte coproporphyrinogen oxidase activity was undetectable in the patient during this attack, and was reduced in his mother, a latent case. The complex relationship between porphyria, epilepsy, and anticonvulsant drugs is discussed.