A turn-on fluorescent sensor for Cd2+ and sequential detection of S2− using the quinolimide scaffold. (27th August 2022)

• Record Type: Journal Article
• Authors: Li, Lan; Zhang, Yu; Yang, Jianhua; Qu, Wenjing; Cao, Hongjie
• Is Part Of: Tetrahedron. Volume 121(2022)
• Publication Date: 2022-08-27
• Subjects: Quinolimide -- Sensor -- Cd2+ -- S2-; Chemistry, Organic -- Periodicals; 547.005
• DOI: 10.1016/j.tet.2022.132917
• Languages: English
• ISSNs: 0040-4020

Abstract

Abstract: A novel quinolimide derivative (BNAL ), bearing the amide-DPA receptor at position 9 of the heterocyclic ring, was synthesized for sequential detection of Cd 2+ and S 2− . BNAL could discriminate Cd 2+ from Zn 2+, showing the turn-on response upon interaction with Cd 2+ . After adding S 2−, the fluorescence of the BNAL -Cd 2+ solution was reverted through the displacement strategy. The limits of detection (LODs) of BNAL for Cd 2+ and the BNAL -Cd 2+ complex for S 2− were found to be 17.9 nM and 1.51 μM, respectively. Finally, cell imaging experiments showed BNAL could be successfully employed for sequentially imaging Cd 2+ and S 2− via the off-on-off behavior in yeast cells. Graphical abstract: Image 1