Juvenile polyposis: Focus on less described manifestations. (June 2022)

• Record Type: Journal Article
• Authors: Saurin, Jean-Christophe; Calavas, Laura; Caillot, Claire
• Is Part Of: Best practice & research. Volume 58/59(2022)
• Publication Date: 2022-06
• Subjects: Polyposis -- Juvenile -- Cancer -- Hereditary haemorragic telangiectasia; Gastroenterology -- Periodicals; Gastrointestinal system -- Diseases -- Periodicals; Gastrointestinal Diseases; Gastroenterology; Klinische geneeskunde; Gastro-enterologie; Gastroenterology; Gastrointestinal system -- Diseases; Periodicals; 616.33005
• DOI: 10.1016/j.bpg.2022.101802
• Languages: English
• ISSNs: 1521-6918

Abstract

Abstract: Juvenile polyposis represents an heterogeneous disease as different genetic dominant backgrounds have been evidenced leading to different clinical presentations. It is associated in some patients with a different syndrome, Hereditary Hemorragic Telangiectasia, justifying a complementary and different management. Recent international recommendations help in managing this very rare disease, and this management should probably be restricted to expert centers able to take care of the multiple manifestations and risks of these patients and families. This paper will focus on the poorly known and evaluated aspects of juvenile polyposis, excluding the colonic involvement and epidemiology that are addressed in a different article of this issue.