Concentrations of vitamins A, C and E in elderly patients with Parkinson's disease. Issue 802 (August 1992)

• Record Type: Journal Article
• Authors: King, D.; Playfer, J. R.; Roberts, N. B.
• Is Part Of: Postgraduate medical journal. Volume 68:Issue 802(1992)
• Page Start: 634
• Page End: 637
• Publication Date: 1992-08
• Subjects: Medicine -- Periodicals; 610
• DOI: 10.1136/pgmj.68.802.634
• Languages: English
• ISSNs: 0032-5473

Abstract

Abstract : Concentrations of the naturally occurring antioxidant vitamins A, C and E were measured in 27 patients with Parkinson's disease and 16 age-matched control subjects, from a similarly disabled patient group. There was no significant difference in the serum concentrations of vitamins A and E in the two groups. Vitamin C was significantly higher (P < 0.05) in the Parkinson's disease group, however, the mean leucocyte vitamin C concentration in the control group was low (101 nmol/10(8) WBCS) compared to established data in healthy young individuals (119-301 nmol/10(8) WBCS). There was no correlation between the severity or duration of Parkinson's disease and concentrations of vitamins A, C and E. There is therefore no evidence from this study that a deficiency of these antioxidants contributes to the onset or progress of Parkinson's disease.