Non-invasive diagnosis of portal vein occlusion by radionuclide angiography. Issue 12 (December 1992)

• Record Type: Journal Article
• Authors: MacMathuna, P; O'Connor, M K; Weir, D G; Keeling, P W
• Is Part Of: Gut. Volume 33:Issue 12(1992)
• Page Start: 1671
• Page End: 1674
• Publication Date: 1992-12
• Subjects: Gastroenterology -- Periodicals; 616.33
• DOI: 10.1136/gut.33.12.1671
• Languages: English
• ISSNs: 0017-5749

Abstract

Abstract : The accuracy of non-invasive radionuclide angiography in detecting portal vein occlusion was assessed in 61 patients--10 with portal vein occlusion confirmed by conventional portography, 25 with chronic liver disease and a patent portal vein (mild = 12, severe = 13), and 26 with normal liver function, who served as controls. The median percentage portal venous flow for the portal vein occlusion group was 8% (range 1-30) (consistent with negligible flow) compared with 78% (52-87) for control subjects (p < 0.005) and 68% (61-80) and 49% (23-59) respectively for patients with mild and severe liver disease (p < 0.001 and p < 0.005). At a portal venous inflow of < 20%, the procedure had a specificity of 100% and sensitivity of 90% in diagnosing portal vein occlusion. Non-invasive radionuclide angiography provides a safe and accurate screening method for evaluating portal vein patency or occlusion in the investigation of portal hypertension or before liver transplantation.