Retrospective study of histological features of acute rejection in renal allografts and comparison with circulating T cell populations. Issue 8 (August 1985)

• Record Type: Journal Article
• Authors: Wyatt, J; Aparicio, S R; Guillou, P
• Is Part Of: Journal of clinical pathology. Volume 38:Issue 8(1985)
• Page Start: 858
• Page End: 863
• Publication Date: 1985-08
• Subjects: Pathology -- Periodicals; Pathology, Molecular -- Periodicals; 616.0705
• DOI: 10.1136/jcp.38.8.858
• Languages: English
• ISSNs: 0021-9746

Abstract

Abstract : The histological severity of acute rejection in renal allografts was determined for 39 rejection episodes in 30 renal transplant recipients. Data were compared with the peripheral blood T cell subset ratios measured before and at the onset of the rejection episode. T cell subset ratios showed no correlation with the histological severity of rejection, nor with the reversibility of the rejection episode. The grade of histological rejection on biopsy was predictive of graft survival. We conclude that renal biopsy remains the best method for determining the severity and outcome of acute allograft rejection episodes.