Dominantly inherited Alzheimer's disease: cerebral glucose metabolism. Issue 6 (June 1987)

• Record Type: Journal Article
• Authors: Polinsky, R J; Noble, H; Di Chiro, G; Nee, L E; Feldman, R G; Brown, R T
• Is Part Of: Journal of neurology, neurosurgery and psychiatry. Volume 50:Issue 6(1987)
• Page Start: 752
• Page End: 757
• Publication Date: 1987-06
• Subjects: Neurology -- Periodicals; Nervous system -- Surgery -- Periodicals; Psychiatry -- Periodicals; 616.8
• DOI: 10.1136/jnnp.50.6.752
• Languages: English
• ISSNs: 0022-3050

Abstract

Abstract : Cerebral glucose metabolic rate (CMRGlu), measured by positron emission tomography, was bilaterally and symmetrically reduced in two patients with autosomal dominant Alzheimer's disease. Supramarginal gyri and temporal lobes were most severely affected. An isolated reduction of CMRGlu in the left supramarginal gyrus was observed in one asymptomatic at-risk subject.