Cyclosporin A in steroid-sensitive nephrotic syndrome with frequent relapses. Issue 743 (September 1987)

• Record Type: Journal Article
• Authors: Chan, M. K.; Cheng, I. K.
• Is Part Of: Postgraduate medical journal. Volume 63:Issue 743(1987)
• Page Start: 757
• Page End: 759
• Publication Date: 1987-09
• Subjects: Medicine -- Periodicals; 610
• DOI: 10.1136/pgmj.63.743.757
• Languages: English
• ISSNs: 0032-5473

Abstract

Abstract : Eight patients with steroid-sensitive nephrotic syndrome which frequently relapsed despite cyclophosphamide treatment were given cyclosporin A (7.5 mg/kg/day to 10 mg/kg/day) for 8 to 12 weeks. Six had minimal change glomerulonephritis and two had focal segmental glomerulonephritis. Cyclosporin A was given to 5 patients when their nephrotic syndrome was in relapse and to 3 patients when the nephrotic syndrome was in remission. Cyclosporin A induced a transient remission in only one patient.