A placebo-controlled blind trial of cyclosporin-A in prevention of corneal graft rejection in rabbits. Issue 5 (May 1982)
- Record Type:
- Journal Article
- Title:
- A placebo-controlled blind trial of cyclosporin-A in prevention of corneal graft rejection in rabbits. Issue 5 (May 1982)
- Main Title:
- A placebo-controlled blind trial of cyclosporin-A in prevention of corneal graft rejection in rabbits.
- Authors:
- Bell, T A
Easty, D L
McCullagh, K G - Abstract:
- Abstract : Cyclosporin-A (CyA) administered to rabbits intramuscularly in a dose of 25 mg/kg/day for 14 days following interlamellar corneal grafting had a significant effect in preventing rejection of the corneal graft (p less than 0.05), and the benefit was maintained. Rejection was attended by an initial mild inflammatory reaction and followed by a protracted intense response involving a variety of cell types, with subsequent loss of epithelium. endothelium and keratocytes, and the development of areas of stromal necrosis. CyA suppressed this rejection response.
- Is Part Of:
- British journal of ophthalmology. Volume 66:Issue 5(1982)
- Journal:
- British journal of ophthalmology
- Issue:
- Volume 66:Issue 5(1982)
- Issue Display:
- Volume 66, Issue 5 (1982)
- Year:
- 1982
- Volume:
- 66
- Issue:
- 5
- Issue Sort Value:
- 1982-0066-0005-0000
- Page Start:
- 303
- Page End:
- 308
- Publication Date:
- 1982-05
- Subjects:
- Ophthalmology -- Periodicals
617.7 - Journal URLs:
- http://bjo.bmj.com/ ↗
http://bjo.bmjjournals.com/ ↗
http://www.bmj.com/archive ↗ - DOI:
- 10.1136/bjo.66.5.303 ↗
- Languages:
- English
- ISSNs:
- 0007-1161
- Deposit Type:
- Legaldeposit
- View Content:
- Available online (eLD content is only available in our Reading Rooms) ↗
- Physical Locations:
- British Library DSC - BLDSS-3PM
British Library HMNTS - ELD Digital store - Ingest File:
- 23708.xml